It does not currently support importing data from compact disc or dealing with CT series larger than 500 images. The latest version of OsiriX Lite has several limitations. As with OsiriX, we can navigate within the virtual bronchoscopic tree using the “three-dimensional mouse button” function and reconstruct virtual bronchoscopic images and movies while referring to the multiplanar reconstruction computed tomographic images Axial, coronal, and sagittal multiplanar reconstruction computed tomographic images and the virtual bronchoscopic image are shown on a screen. Reconstructing virtual bronchoscopic images by Horos. The virtual bronchoscopy procedure using Horos is almost same as that using OsiriX. We could export the virtual bronchoscopic data as a video using the “fly-thru” function. We could move freely within the 3D virtual bronchial tree using the mouse buttons. The chest CT images were automatically converted to a bronchoscopic view using the “3D endoscope” function in Horos. DICOM data from patients' chest CTs derived using lung window without contrast were copied to a computer. Horos version 4.0 was installed on a Mac Mini 2018 with OS 10.15 Catalina software (Apple, Cupertino, CA). We applied Horos to virtual bronchoscopy. Recently, Horos has been used to analyze both 2D and 3D CT images. Like OsiriX, Horos can be used to perform three-dimensional (3D) reconstruction of computed tomography (CT) images. Horos™ (Horos Project, Geneva, Switzerland) is a free DICOM viewer for Mac OS X based on OsiriX 5.8, the latest open-source version of OsiriX. OsiriX Lite, the complete demo version, is still free, but it has various functional limitations.

Although the 32-bit version of OsiriX was free, OsiriX recently ceased to be an open-source software. Previous studies have reported the use of virtual bronchoscopy involving OsiriX™ (Pixmeo, Geneva, Switzerland), an open-source DICOM viewer for Mac OS, and its application for transbronchial biopsy and surgery.

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